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doi:10.3390/ijms24043098 106

in: PubMed | Google Scholar | 1 The First Affiliated Hospital of Jinan University, Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of the Chinese Ministry of Education, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, and The Sixth Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China

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Furthermore, excessive accumulation of iron and copper induced by periodontal pathogens could damage the antioxidant system in the periodontium, ultimately resulting in ferroptosis and cuproptosis during periodontitis